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RHR: The Link Between Metabolic Health and Mental Well-Being, with Dr. Matt Bernstein

November 18, 2025
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In this episode we discuss: Recent studies on the relationship between ketogenic diet and mental health conditions The mechanics of how ketones affect the brain Considerations for treating mental illness in kids and teens What are the target therapeutic ketone levels and how supplementation can help Using ketogenic diets to address behavioral disorders Show notes: [embedded content] Hey everybody. Chris Kresser here, welcome to another episode of Revolution Health Radio. I’ve talked on the show before about the link between metabolism and mental health. In fact, I had Harvard psychiatrist Dr. Chris Palmer, who’s been a pioneer in this field, on the show, to talk about metabolic psychiatry and his brain energy theory of mental illness. So I was really excited to welcome Dr. Matt Bernstein as a guest on the show...

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RHR: From Wired & Tired to Calm & Clear: My Top Nutrients for Mood, Focus, and Sleep

October 28, 2025
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In this episode we discuss: Why we need better solutions for stress and sleep Saffron – The mood-boosting spice for stress relief L-Theanine – Finding calm focus (zen in a teacup) Lemon balm – Nature’s gentle tranquilizer for anxious minds Holy basil – A sacred adaptogen for calm and clarity Ashwagandha – The adaptogen for resilience and restful sleep The synergistic effect of combining these nutrients for maximum benefit Show notes: “The possible “calming effect” of subchronic supplementation of a standardised phospholipid carrier-based Melissa officinalis L. extract in healthy adults with emotional distress and poor sleep conditions: Results from a prospective, randomised, double-blinded, placebo-controlled clinical trial” by Bano et al.  “The effects of lemon balm (Melissa officinalis L.) on depression and anxiety in clinical trials: A systematic review and meta-analysis” by Ghazizadeh et al.  “The combination...

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RHR: The Science Behind Oral Inflammation, with Dr. William Levine

October 7, 2025
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In this episode, we discuss: How periodontal disease develops and impacts the body Recognizing symptoms of periodontal disease Conventional and modern treatments for standard chronic periodontal disease How to prevent gum disease Emerging technologies in periodontal care The future of frequency medicine and personalized care Show notes: [embedded content] Hey everyone, Chris Kresser here. Welcome to another episode of Revolution Health Radio. Over the years, I’ve talked about the importance of oral and periodontal health, not just for the health of our teeth and our mouth, but for our overall health. We now know that there’s a strong connection between periodontal disease and everything from heart disease to autoimmune conditions, because the bacteria in the mouth can get into the bloodstream and then provoke a systemic inflammatory autoimmune reaction. Today I’m really excited...

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Hyaluronic Acid: The Deep Hydration Molecule Your Skin Has Been Waiting For

September 3, 2025
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If you’ve spent any time exploring the world of natural skincare, chances are you’ve heard of hyaluronic acid (HA). Once confined to topical serums and dermatology clinics, HA is now making waves as an oral supplement that nourishes your skin from the inside out. And for good reason: this remarkable molecule doesn’t just hydrate—it rejuvenates, heals, and protects, making it one of the most essential tools in your inner beauty toolkit. What Is Hyaluronic Acid? Hyaluronic acid is a naturally occurring polysaccharide—a long-chain sugar molecule—found in high concentrations in the skin, joints, and eyes. Its superpower? Holding up to 1,000 times its weight in water. In the skin, HA resides primarily in the dermis, where it acts like a sponge, attracting and retaining moisture to keep tissues...

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Rice Ceramides: The Unsung Hero of Skin Hydration and Barrier Health

August 29, 2025
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We often think of radiant skin as the result of what we put on it: moisturizers, serums, masks. But emerging science and clinical practice tell a different story. True skin health starts from within. And when it comes to supporting that inner foundation, few ingredients are as compelling—yet underappreciated—as rice ceramides. What Are Rice Ceramides? Ceramides are lipid molecules that serve as key structural components of the skin’s outermost layer, the stratum corneum. They act like mortar between bricks, sealing in moisture and protecting against environmental irritants. Without adequate ceramides, the skin barrier weakens, leading to dryness, sensitivity, and accelerated aging. Rice ceramides, specifically glucosylceramides and elasticamides derived from rice bran, are natural plant-based ceramides that can be consumed orally. Unlike topical creams, which provide temporary moisture, oral...

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Lutein and Zeaxanthin: The Carotenoids That Protect and Perfect Your Skin from Within

August 25, 2025
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When most people think of lutein and zeaxanthin, they picture eye health supplements or leafy green vegetables. But these vibrant carotenoids are now gaining attention for another powerful role: enhancing and protecting the skin from the inside out. With their impressive antioxidant, photoprotective, and skin-brightening properties, lutein and zeaxanthin are essential components of any beauty-from-within strategy. What Are Lutein and Zeaxanthin? Lutein and zeaxanthin are fat-soluble antioxidants from the carotenoid family, naturally found in marigolds, leafy greens like spinach and kale, and colorful fruits and vegetables. These nutrients are not produced by the human body, so they must be obtained through diet or supplementation. What sets them apart is their ability to accumulate in tissues rich in lipids and oxidative stress—like the macula of the eye and the...

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Vitamin C: The Collagen-Stimulating, Skin-Brightening Antioxidant Your Skin Can’t Live Without

August 22, 2025
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When it comes to supporting skin health from the inside out, few nutrients are as essential—or as well-researched—as vitamin C. This water-soluble vitamin, also known as ascorbic acid, plays a crucial role in maintaining youthful, radiant skin. From stimulating collagen production to protecting against environmental damage and evening out skin tone, vitamin C is a cornerstone of any natural beauty strategy. What Is Vitamin C and Why Is It Crucial for Skin? Vitamin C is a potent antioxidant that also functions as a critical cofactor in many enzymatic reactions throughout the body. Humans, unlike most animals, cannot synthesize vitamin C on their own. This means we must obtain it through food or supplementation. In the skin, vitamin C is concentrated in the epidermis and dermis where it supports...

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Eggshell Membrane Collagen: A Natural Ally for Skin, Hair, and Nail Vitality

August 20, 2025
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In the growing world of natural beauty and inside-out skincare, few ingredients offer the versatility and clinical backing of eggshell membrane (ESM) collagen. While it might not be the first compound that comes to mind when you think about radiant skin or strong nails, emerging research shows that this humble, upcycled byproduct is a powerhouse for restoring and maintaining healthy, youthful skin, fuller hair, and resilient nails. What Is Eggshell Membrane Collagen? Eggshell membrane is the thin, filmy layer you find between the shell and the egg white. Though often discarded in food production, it turns out this natural material is packed with biologically active nutrients: multiple types of collagen (I, III, V, X), elastin, hyaluronic acid, glycosaminoglycans (GAGs), and keratin precursors. These are the same building...

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Biotin: The Essential Nutrient for Stronger Hair and Healthier Nails

August 18, 2025
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If you’ve ever scanned the beauty aisle or browsed wellness forums, you’ve probably seen biotin pop up again and again as the go-to vitamin for strong nails and luscious hair. Often referred to as vitamin B7, biotin plays a vital role in the health and resilience of keratin-based structures—including your hair, nails, and skin. But beyond the hype, what does the science say about biotin, and how can you use it effectively to support your natural beauty? What Is Biotin? Biotin is a water-soluble B-complex vitamin that functions as a coenzyme in several essential metabolic reactions. It helps convert carbohydrates, fats, and proteins into usable energy and plays a direct role in the synthesis of fatty acids and amino acids—both critical for the formation of keratin, the...

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RHR: Beauty From Within – Why Radiant Skin, Hair, and Nails Start Inside

August 5, 2025
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In this episode, we discuss: Why internal health is the key to external beauty Biotin – the hair, skin & nails vitamin Vitamin C – the collagen booster and antioxidant Hyaluronic acid for deep hydration from within Rice ceramides for sealing in moisture and smoothing skin Eggshell membrane collagen for stronger skin, fuller hair, and tougher nails Lutein and zeaxanthin – skin’s natural UV shield and glow enhancers Show notes: “Small Intestinal Bacterial Overgrowth in Rosacea: Clinical Effectiveness of Its Eradication” by Parodi et al “Acne vulgaris, probiotics and the gut-brain-skin axis: from anecdote to translational medicine” by W. Bowe and A. Logan “The Gut-Skin Connection: How Altered Gut Function Affects the Skin” by Chris Kresser RHR: Understanding the Gut-Brain-Skin Axis podcast episode “Association of diet with acne vulgaris among adolescents in Ibadan, southwest Nigeria” by Okoro et...

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